This course provides a comprehensive overview of the pathophysiology, epidemiology and clinical signs and symptoms associated with disorders of the various bodily systems and the musculoskeletal pathologies that manifest from them. The implications for physical therapy, medical management and pharmaceutical interventions of these disorders will be discussed. Students will apply clinical reasoning and the latest research and evidence to differentiate disorders that originate within the neuro-musculoskeletal system, in addition to screening for serious pathology.