Winter quarter of this two-quarter course uses a didactic approach for a comprehensive coverage of medical microbiology. This course sequence includes discussion of basic classification, structure, metabolism and genetics of bacteria, viruses, parasites, and fungi, as well as discussion of individual pathogens in the context of infectious disease. The infectious disease portion of each course uses an organ systems approach, focusing on basic morphologic, culture and diagnostic modalities, physiology, virulence determinants, epidemiology, host-pathogen interactions, and management of disease with special emphasis on factors pertinent to clinical medicine and public health. Clinical correlations and case presentations are featured for each organ system.